Tottenham manager Antonio Conte is facing the prospect of having only 13 players, including two goalkeepers, available for training ahead of Thursday's fixture against Leicester City.
According to reports in The Telegraph, Spurs have been hit by a new positive Covid-19 case among their first-team squad, with the north Londoners also recording more cases among their Under-23s.
Tottenham were forced to postponed their Europa Conference League match with Rennes last week and Sunday's Premier League visit to Brighton & Hove Albion.
As it stands, their trip to the King Power Stadium on Thursday is still scheduled to go ahead, although it is unclear exactly how many players Conte will have at his disposal.
Eight first-team players, nine members and staff and a host U23 players tested positive for the virus last week, and while it is unclear what the figure is now, there has reportedly been a new case among the first-team.
The Telegraph also states there has been a large outbreak among the Under-23s, meaning Conte is unlikely to be able to boost the number of players available to him.
Tottenham reopened a part of their training ground for a limited session on Sunday, suggesting the Italian boss is trying to prepare a team for the game against Leicester.
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But that appears increasingly difficult with fears over whether more members of the squad will be affected following a new positive case among the first-team.
Spurs are not the only club facing Covid-19-related problems.
Manchester United have also suffered a coronavirus outbreak among their squad and have closed down their training ground for 24 hours as a precaution.
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The Red Devils are in talks with the Premier League over their visit to Brentford on Tuesday.
Aston Villa also shut their Bodymoor Heath training complex on Sunday after one player and some staff tested positive
Meanwhile, Queens Park Rangers have postponed their game against Sheffield United on Monday night after an outbreak within their ranks.
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